Pet friendly hotels in somerset pa

TLDR: close group of professional friends, not sure if people are haters or our behavior is genuinely too much
I’m in grad school and so are a whole group of my friends. Before matriculating though, a bunch of us went through a program that kinda preps first generation students for the rigors of academia. It was a hellish experience tbh and involved some of the most traumatic collective experiences most of us have had in academia (like straight up, there were deaths in nearly all of our lives/families/friend groups that we couldn’t attend to, someone almost died because of academic demands, there were sexual assault attempts, systemic violence). And because of that, combined with our determination to get through it all anyway, a big group of us trauma bonded and stayed friends when we all went our separate ways. We talk almost every day and have become actual friends.
Earlier this year, there was a leadership conference with an election for membership on the board of a particular professional organization and it was the first time we all got together as a group. It was a hard time for us because we had to gather in the same place and see many of the same people that traumatized us, but we also had an election to run. It ended up being highly contentious, so we decided early that the best thing to do would be to openly support eachother and eachother’s friends (or rather, highly respected but enjoyable colleagues) and other people who seemed amenable to our style of doing things (specifically: no dirty tricks, running from a place of community, support, and good clean positivity) and campaigning as a large group. Other people did try to be kinda underhanded about it, which only strengthened the bond between us, our new members in our group and our supporters.
We won, of course. We are all super qualified, charismatic, hard working people who know how to rally support.
The rest of the conference, we just had fun while also networking, attending events and trying to work through some complicated feelings. But because our group was big and we were at all the good parties and we almost always traveled with someone else from our group, and because very influential people in our field like us, people started getting weird about it. People were jealous that there was no room at our table because high profile academics were sitting with us. We were more outgoing than everyone else and people from our schools were jealous that we weren’t spending more time with them. One night after a very draining day, we decided to all have a moment alone to decompress at our favorite bar and it’s a cool bar so of course we took snaps. We have tried to be inclusive and make a lot of friends and meet everyone, but that seems to only worsen the jealousy when we’re successful.
One of the influential people we’re all close with told us that people were starting to refer to us as a cult, and months after, that reputation has stuck. People talk about how we all talk every day, how we hype each other up on socials and networking sites, how we all party together when we’re in the same cities and often end up collaborating. The fact that we are also all highly motivated and successful people who get asked to do elite things (which means we travel a lot and get to do cool things together) hasn’t helped. To their credit, I will admit we are maybe too comfortable with each other: we try each other’s drinks and food, I let people nap in my bed if i’m not there or drive my car or shower in my hotel room (I always get my own room).
To be honest, this is all super funny to me because we’re just chill people who want to do good in our field and happen to like each other but the fact that it’s spreading beyond our immediate circle has me wondering if it’s actually not funny. Like, is it really that dickish to be bonded to people you work with? Or is this just high school behavior and it comes with the territory?

 I wanted my gf (20) me (19) back, together for 2 years. I was texting her everyday after it happened trying to forgive her for what she did. She was ghosting me when I left her and l broke up with her because she took my sister to a hotel room with an older man and lied to me about the whole Situation. then she started trying to get back with me. Putting in effort to sort of and came to see me a couple times. She called me one night saying she had the clap and had given me it. I asked how’d you get it and she tried saying it was me because a girl I worked with gave it to us the first week we got together. Then she said she hasn’t don’t anything. Her friend tells me the following week that she had a threesome together and that she’s been doing coke and all this shit. So I asked her, she confirmed it. I told her I don’t want to keep talking to her and that I need time to forgive her and that i did and I could still be her best friend because she’s all that I had, that is all. She said talk to me when you’re ready. I called her two nights ago. She didn’t pick up. She called me the next day and said she saw my calls and didn’t do anything. I thought nothing of it. I called her talked to her yesterday and she was saying all this stuff like begging for me back saying I was all she wanted. So we continued talking this night. Then something was said and she got upset and told me she was with a man that I know, the night I called her. That she did coke with him then got a hotel room with this other man and sucked him off. I told her I forgive her for why she did it and that I didn’t want to speak to her again. I blocked her on everything. She somehow was able to keep calling me, I entertained it so I could get some sleep for my job Tomorrow it was 5am and had work at 10am. she was telling me she would drop everyone for me if I wanted her. I said if you wanted me you would have already done that. Eventually I said yeah I want you just so I could get some sleep because she wouldn’t leave me alone. I don’t know how to feel with this whole mess. I deserve so much more then this, I hate it so much. I want to know if anyone else could put their self in my shoes and could forgive this women or just call it the end to get self care. 

Im traveling in another country at the moment in Latin America. I was fairly drunk this weekend when I met a girl at a bar, we clicked. We were laughing, touching, pretty much everything but when I asked her to come back to my place, she said she couldnt go because she was with her friend. But she promised we would see each other again and exchanged numbers.
After saying bye, I started walking down the street of bars, and to which she followed me saying she needed to charge her phone. We saw a hotel nearby and asked them if she could charge it, and the clerk told her she can charge it if we rent a room for an hour. Apparently this was a love hotel, a hotel where you could "rent" by an hourly rate.
Well, we both ended up just renting the room so we can lay down and charge her phone. Immediately when we entered the room we started kissing when the door shut and before you know it she was sucking my cock and i was slapping her in the face with it. I told her to get on all fours on the edge of the bed, to where i started fucking her hard.
This is when the tequila demons summoned this dirty talk out of me. As I was pounding her from behind in this position I said "Did you think you were going to be fucking me like this right now?! Huh?" "We just met and i got you on all fours taking my dick" "Did you think i was the type of guy to fuck you this way?" things like that. It really raised the temperature up a lot. 1 hour was not enough for us, as the room ended and it was really late and i decided to go home.
I guess i really thought she wasnt interested when i walked away and the charger thing was completely unplanned because if we didnt see this hotel she wouldve most likely just went to another bar to charge her phone.
Were meeting up again this week and i cant stop thinking about how hot it was to talk to her like that. She kept sending me nudes after and told me she wants to see me asap
What kind of dirty talk is this?

I apologize this is so long, but really needed to vent. I made plans to travel with some friends over the Memorial Day weekend to Washington, DC. I'll call them Friend A and Friend B.
Both of them wanted us to meet at a store parking lot to go on the road trip together. I thought we were meeting at my house which is 15 minutes away from that store, but Friend A influenced Friend B to change these plans the night before the trip. I didn't want to leave my car in a public parking area where it may be towed. So, I offered gas money to Friend B driving to be picked up by him, and I said Friend A could park his car at my place. Friend A said it didn't make any sense, he didn't care about leaving his car at the store, and they weren't going to pick me up since it's out of the way. It was also too late for me to cancel the trip since I put a deposit down for my hotel. I ended up paying for an $18 Uber to meet them at the store. I was a bit angry, but dropped it.
When we got to the hotel, there was a bed bug on the bed, so I switched to a new hotel room. After that, we had a great night dining downtown and walking around the city.
On Saturday, we made plans to meet for breakfast, so I told both friends that I was getting ready and what time I'd be downstairs. The time came and went, and they weren't ready. I went on my own and got breakfast.
Friend B called at 12:30pm, saying he and Friend A went to another breakfast place nearby since they didn't like the food where I went. They also wanted to meet around 1pm to go around DC for sightseeing. 1pm came and went, and I finally called them at 2p. They said they went to get some items from a store and to meet in the lounge area of our hotel outside. We finally met at 3p, and I said I didn't want to hang around the hotel all day. Friend A said he had some people in the area that he was waiting to hear from, which is why we didn't go anywhere most of the day.
We finally left the hotel late in the afternoon and went to the park, and then a restaurant. I was annoyed. Later after dinner, we walked around and did nothing fun or any sightseeing. I decided to go back to the hotel since my stomach felt overstuffed, so I called it a night. They decided to stay out and drink alcohol.
The next day, we rode back home. I asked Friend B if he could drop me off at my house since it's only 15 minutes away from our original meeting point. He then asked Friend A if he could do it instead, and he said okay. Then about 30 minutes away from the meeting point, Friend A said I should've parked my car (for the 5th fucking time) at the grocery store so I could drive myself back.
At the end of the car ride, Friend A told me he couldn't take me back home after all and said good luck-- no apology, just a stupid attitude. I told him to piss off and just grabbed my stuff, preparing to call an Uber. Then Friend B told me he'd take me back. I was extremely angry by the time I came home that I had wasted time and money on this trip. I cut off communication with them on the phone and social media since I thought they treated me like garbage. I'm not sure about continuing my friendship with them, especially Friend A since I was angry with him a few months ago for something similar to this. We're part of a bigger circle of friends, which makes this awkward. I'm so upset right now.

As I head back to the Cancun airport here are my sentiments I take away most from the experience:
No where near as dangerous as online made it seem. Stuck to mostly tourist areas but definitely good to have situational awareness when venturing out.
The hospitality of Tulum was like no other. The people are friendly, hospitable, and service is next level experience.
Expensive, expensive, expensive. Probably the most I spent on a trip. But then again we went for the 1st class experience with boutique jungle theme hotel on water, and five star restaurants. You can easily drop $200 dinner for one at a top restaurant. But you can expect the most spectacular show like a Mayan fire performance comparable to a Vegas show. The quality of the food is out of this world. I think I ate the best steak I ever had in my life at Bak.
Vendors, yes annoying. You constantly feel harassed like every other minute on the beach. But do yourself a favor and spend the $10 on a 50 cent bracelet. You will make a 5 year old girl’s day.
Swim with the alligator, snorkel through the bat infested caves of the cenotes even if feeling reminiscent of one of those horror flicks where they discover some terrifying new species deep within lol. Learning the Mayan rituals history despite its gruesomeness was magical to be there.
I hate im too cheap to buy one of those beautiful Mayan style dresses but if any locals have insider tips for an online store I can get cheaper lol help a girl out.
I’m sad for the Mexican people that the only beach area I witnessed the locals enjoying was this rough area with stones and boulders whilst the tourists enjoyed the pretty sandy beaches. Yes the sargassum is bad, doesn’t smell. You can find some areas cleaned daily by the resorts. The water is nice.
I think if I were to visit again I would find an Airbnb, rent a car, eat the street food, and venture out. We were two girls English speaking only so played it safe going into this. So much development going on in Tulum, I can only imagine what it will be like in ten years, better or worse. I definitely appreciate the experience.

I have been having a really hard time finding women I vibe with. I feel there is nobody who is into trans women physically and I am losing hope. I am located in Illinois but willing to relocate so could start something online.
I am loving, confident, fun, silly, outgoing, caring, compassionate and I will do anything I can to please my partner. I am a caregiver by choice in my career - registered nurse. I love to care for others and I love opening up and offering myself to others wants and needs.
I am open to anyone 20+ as long as we can vibe. I feel like I often have a younger attitude as I am trying to relive my college days in a way I am sad I missed out on. About me: I am a registered nurse in an emergency room, my hobbies and interests include fashion, video games, shopping, traveling domestic and international, I love cuddling, Netflix/entertainment in general, and fantasizing about how amazing life would be if I were more beautiful. I have 3 sisters and come from a pretty conservative family. I can’t stand Donald Trump and no I don’t need any negative messages about why. If you are a Trumper please refrain from messaging me (I doubt there’s many here anyways). I tend to have sexual desires, fantasies, and just daydream about dates and things I wish could happen. I can also totally refrain from this is if this is nothing you’re interested in but I wouldn’t mind having a BFF 👯‍♀️ to share experiences and secrets with. I think a relationship is best started as a friendship then grows, so let’s just chat and see where things go.
I love pets but don’t have any of my own, taking care of myself is a big enough responsibility 😆. I have plenty of other interests and would love to make friends or more seeing if it goes that way. If you want to be friends or just think I’m cute let’s chat 😘 (pics in my profile).

I have been having a really hard time finding women I vibe with. I feel there is nobody who is into trans women physically and I am losing hope.
I am loving, confident, fun, silly, outgoing, caring, compassionate and I will do anything I can to please my partner. I am a caregiver by choice in my career - registered nurse. I love to care for others and I love opening up and offering myself to others wants and needs.
I am open to anyone 20+ as long as we can vibe. I feel like I often have a younger attitude as I am trying to relive my college days in a way I am sad I missed out on. About me: I am a registered nurse in an emergency room, my hobbies and interests include fashion, video games, shopping, traveling domestic and international, I love cuddling, Netflix/entertainment in general, and fantasizing about how amazing life would be if I were more beautiful. I have 3 sisters and come from a pretty conservative family. I can’t stand Donald Trump and no I don’t need any negative messages about why. If you are a Trumper please refrain from messaging me (I doubt there’s many here anyways). I tend to have sexual desires, fantasies, and just daydream about dates and things I wish could happen. I can also totally refrain from this is if this is nothing you’re interested in but I wouldn’t mind having a BFF 👯‍♀️ to share experiences and secrets with. I think a relationship is best started as a friendship then grows, so let’s just chat and see where things go.
I love pets but don’t have any of my own, taking care of myself is a big enough responsibility 😆. I have plenty of other interests and would love to make friends or more seeing if it goes that way. If you want to be friends or just think I’m cute let’s chat 😘 (pics in my profile).

I'm not having compassion fatigue, but I'm going through something. I don't know what else to call it other than hyper-empathizing with dogs/cats(and less with humans) . I am 10 years in and started working at shelteHVLC practice about 3 months ago.
I'm seeing A LOT that I've never seen before. It started when moved to southern Alabama last year and worked as a tech(after getting out of an abusive relationship). I saw things there that I never came across in NJ/PA,where im from. It was common to see dead dogs on the side of the road where I was in Alabama.
I moved back up north and started working where I am now. I'm seeing and hearing abandonment and abuse cases often. I am now empathizing with even very aggressive dogs and cats. I feel like I understand them more than humans.
I am OK, but wondering if anyone has felt like this.? I feel like my personal life (and recent past) definitely contributes to this. I now have pets, where before, I did not . The first 7 years as a tech, I was very far removed from animals and honestly not that compassionate. Now I'm a damn sucker for even the worst behaving fur babies.

Currently, NWBO's Sawston plant is the only visible global hub for DC VAX L manufacturing and distribution (MHRA MIA approval 3/20/23) . For $400 , FED EX (https://www.fedex.com/en-us/custom-critical.html) ships anywhere globally within the required timeframes.A SAGE (https://journals.sagepub.com/doi/10.1177/20363613231179541) 5/26/23 scientific publication demonstrates intent by Pakistani neurosurgeons to treat and cure their GBM patients. Looks like the DC VAX L JAMA paper and LIAU- Bosch presentations since 10/26/22 have created global awareness that DCVAX L will be is a major global cell based biotech therapy, addressing GBM , and all solid tumors( https://conferences.asco.org/am/industry-expert-theater).
With 50% of LIAU-SPORE-UCLA combo patents living 10 years, DC VAX L has turned SOC's GBM treatment from a terminal (16.5) months disease into a chronic treatable malignancy .
Dr. Greg Zivic:
"This treatment can turn a Glioblastoma into a chronic treatable disease even after recurrence of the tumor . "
https://nwbio.com/northwest-biotherapeutics-and-advent-bioservices-announce-receipt-of-license-for-commercial-manufacturing-at-sawston-u-k-facility/
https://twitter.com/AllenTurner206/status/1636426400382205952
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=171479167
Monday, May 29, 2023 9:13:34 AM
Post# 596739 of 596755 4 Pakistani neurosurgeons endorsing the JAMA Liau dc vax l phase 3 study. Will the RA in Pakistan facilitate their patients' resected GBM tumors and lysate being sent to Sawston , with syringes of dc vax l sent back to Pakistan?
https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847
https://journals.sagepub.com/doi/10.1177/20363613231179541
https://pubmed.ncbi.nlm.nih.gov/36591625/
IMO,BB's consultant is a "legend ", as alleged.Therefore, I recommend reading every on of his posts, word for word.
Bright Boy Brian F Egolf Sr M: Bright Boy
Re: ae kusterer post# 593171
Sunday, May 14, 2023 2:22:21 PM
Post# 593185 of 593185 I am definitely not a biotech expert and what I've learned about Northwest and DCVax-l was shared with me by one of the legends in the biotech world !!! My biggest takeaway is this:
From 2018 forward, it became apparent that DCVax-L was a breakthrough, technological process for the treatment of nGBM and rGBM, but its true potential was only known by a "handful" of experts, and as such, the understanding of the broader market implications was a relative unknown. Early on, several of the comments that I heard from BP were," The GBM market is really not that big!" and " Personalized, Immunotherapy vaccines are not really in our 'Wheelhouse'. We sell compounds/pills!!" On and on! The comments didn't mean that BP wasn't paying attention! Quite the contrary, BP was watching like a hawk as results from Dr. Liau and the UCLA trials began to leak into the medical community suggesting a broader application of DCVax-L on a "stand alone" basis and in combination with CI's for all large tumor cancers ( mentioned in the latest 10Q for future trials), thus dramatically expanding market potentials!!! But the "Big Moment" occurred in late October of last year when the STADIUM LIGHTS turned on, shining bright lights on the latest nGBM/rGBM ,Dr. Liau trial data suggesting 50%to 65% OS for 8 years with emphasis on rGBM !!! That was the point in time when BP and the entire biotech world realized that GBM/rGBM would be treated and managed as a CHRONIC DISEASE!!! with unlimited PROMISE and HOPE for patients and unlimited marketing potential to finance existing vaccine production and the continuing development for improved treatments for all diseases!!!!!
So that's what I learned and that's my story and I'm stickin to it!!!!
Cheers especially to all the Mom's and to everyone !!!
BB
Joseph H.Pratt: https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172010930
Bright Boy Re: None Saturday, March 18, 2023 12:38:55 PM Post# of 596750 Go People, People, People !!!!
The light switch just turned on for me !!! I'm not a doctor or scientist or a STEM concentration "rock star", but if I read something over and over again several times and look carefully at the pictures SOMETIMES, NOT ALL THE TIME, a major mental breakthrough occurs and I believe that I've discovered something very profound!!
In this case, I believe the main message from the slide deck is that DCVax-L, either by itself or in combination with CI's has turned the whole thing around for treating nGBM/rGBM from having to kill the tumor to a "management process" !! It looks like now with this new information, that GBM patients can receive vaccinations as needed with "Zero" side effects and live a long and happy life !!! A comment from a medical expert that DOES KNOW !!!:
Dr. Greg Zivic:
This treatment can turn a Glioblastoma into a chronic treatable disease even after recurrence of the tumor.
So help me out here. Does the above reasoning seem logical based on the slides all of us have just reviewed?? If it does or is, then little Team Northwest has just changed the healthcare landscape forever in the way that we treat disease!!!!!
Am I way off base or are all of onto to something that is fabulous beyond belief???
Cheers,
BB
Bright Boy Re: thermopost# 591947 Tuesday, May 09, 2023 8:41:30 PM Post# of 596749 Go The UK is determined to be the world carrousel for use of immunotherapy vaccines to treat cancers and all forms of disease!!! From my friends in the UK, my use of the word "determined" grossly understates the effort behind the "Grand Plan"!!
So far, the MHRA has not only accepted and approved the MIA application (manufacturing license), but voluntarily offered the expansion to a GLOBAL MANUFACTURING" license allowing for the import of live cells and the export of vaccines to the far corners of the earth!!! People!!! That is huge!!!!! BUT as always 99.99% of the retail investors don't understand the significance of that license or anything else about the process and look to the screen to validate the importance/value of the license, where they are greeted by Citadel and Virtu and the rest of the gang that manipulate the price to new lows, confirming that, in spite of everything they just read from the greatest medical minds in the universe, is a bunch of crap!!!!
Fortunately for the cancer patients and shareholders of Northwest, the MHRA does not include in their decision making process the current SP of NWBO or the opinion of the "gutter filth" that manage those companies or any other companies that participate in the ordered destruction of small biotechs that are engaged in the development of immunotherapy vaccines!! So, it's on to the filing of the MAA (marketing license), the approval and the decisions that will guarantee swift treatment deliveries to patients!!
So Griffin and Cifu and Fuerstein and the rest can lie all they want , but the GREAT UNITED KINGDOM will not be denied the ultimate crown of being the WORLD CENTER for CANCER TREATMENT !!!!!
Cheers,
BB
Bright Boy Re: hoffmann6383post# 578889 Tuesday, March 21, 2023 1:55:12 PM Post# of 596749 Go People, People, People!!! It's your friendly "hillbilly" here with some more great news!! Don't know if I can "one up" my earlier post about the "Dog eating the license", but I'll try. So here we go!!
I don't think everyone realizes how dynamic and important the manufacturing license really is so I'll take a shot at giving you my take on it. First of all, the marketing approval (MAA) and the government subsidy approval(NICE) are pretty much in the bag before the manufacturing team gets the "green light" to proceed. The MAA and NICE teams talk to the MIA team and say," This stuff looks really cool and we wanted to let you know before you run off and do a lot of work on something that we won't approve when you're finished!!" Okay! So that's the first part.
Now for the second part and this is the part that involves a lot of money so read very carefully!!! The MIA license allows for global export of the vaccines and global import of immune cells/tumor resected material. Anyone in the entire world that is diagnosed with GBM can NOW ship their tumor samples to Northwest/Advent/Sawston to have their personal vaccine made and stored, all to be shipped back to the patient/doctor on a prescribed injection schedule. The beauty of this process is that patients everywhere can NOW receive their vaccine on a compassionate care basis. No more waiting!! No more opportunities for the "dark forces" to delay or deny suffering cancer patients their desperately needed treatments !!!
People, as of yesterday, Northwest is now IN BUSINESS !!!! AND that opens the door for institutional investors and an uplist to the New York or Nasdaq exchanges!!!!
All of the above is as good as that first sip of ice cold buttermilk on a hot summer day!!!! AND for those unfortunate shorts and haters it adds a whole new description to the letters FTD and I'll let you guess what that might be!!!
Cheers,
BB
Bright Boy Re: None Tuesday, March 21, 2023 9:05:54 PM Post# of 596749 Go The MIA allows for "International Immune Cell Imports" and "International Vaccine Exports" !!! That is big news and a big, big market and should access every cancer patient in need!!!!
Cheers,
BB
ae kusterer
Re: None
Monday, May 29, 2023 9:13:34 AM
Post# 596739 of 596755 4 Pakistani neurosurgeons endorsing the JAMA Liau dc vax l phase 3 study. Will the RA in Pakistan facilitate their patients' resected GBM tumors and lysate being sent to Sawston , with syringes of dc vax l sent back to Pakistan?
https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847
https://journals.sagepub.com/doi/10.1177/20363613231179541
https://pubmed.ncbi.nlm.nih.gov/36591625/
Abstract Objective: To define the landscape of treatment patterns and current epidemiological data regarding gliomas in Pakistan.
Methods: As part of the Pakistan Brain Tumour Epidemiology Study (PBTES), data were collected from 32 neurosurgical centres across the country. Our retrospective study looked at patients who underwent surgical procedures for gliomas in 2019 in neurosurgical centres. The data was collated and analysed using STATA version 15.
Results: A total of 781 patients with gliomas were identified 479(61.8%) in public sector hospitals, 302(39.1%) in the private sector). The most common histopathological subtypes were glioblastoma 262 (33.5%), followed by astrocytoma 147(18.8%) and oligodendroglioma 93(11.9%). Gender distribution was skewed towards men 508(65%). Private institution hospitals performed surgical biopsies as the first surgical procedure 75(23%) more often than public hospitals 38(9%). Chemotherapy was given to 115(29.8%) patients, and there was no data regarding 467(53%) of patients. Similarly, only 202(43.9%) patients received radiation therapy, and there was no data for 469(60%) of patients. For high-grade gliomas specifically, only 95(31.8%) patients with HGG have a record of receiving radiation therapy, and only 57(18.9%) had a record of being started on chemotherapy.
DCvax: A promising advancement in oncology for the treatment of glioblastoma Areeba Fareed https://orcid.org/0000-0001-5906-9852 [email protected], Samia Rohail https://orcid.org/0000-0003-1488-0080, […], and Abdul Moiz Khan https://orcid.org/0000-0001-9796-8867+1View all authors and affiliations All Articles https://doi.org/10.1177/20363613231179541
Contents Declaration of conflicting interests Funding ORCID iDs Footnotes References PDF / ePub More Dear Editor, Glioblastoma is a malignant neoplasm of the central nervous system that arises from glial cells, primarily astrocyctes and is characterized by poorly differentiated, fusiform, round or pleomorphic astrocyctic cells with marked nuclear atypical and brisk mitotic activity.1 Despite advances in early diagnosis and comprehensive treatments, there is nearly 100% recurrence rate and dismal patient survival.2 According to researchers, more than 13,000 Americans are diagnosed with Glioblastoma annually, causing significant morbidity and mortality. There has been no cure for Glioblastoma so far.3 Treatment options often include surgical removal of the tumor followed by concomitant radiation and adjuvant temozolomide TMZ chemotherapy which has been the standard of care for glioblastoma since decades, but exposure to high doses of ionizing radiation is a well-known exogenous risk factor for glioblastoma. The inability to cross the BBB is the major obstacle in achieving remission after surgical resection followed by chemotherapy and radiation.4 As a result, glioblastoma typically recurs within six to 8 months and the survival rate is generally less than 5%.2 Despite the development of novel, complex, multidisciplinary, and targeted therapies the outcome for patients remains almost universally lethal.5 Therefore, the need for effective treatment is undeniable. For this reason, it has been a priority area in cancer research. Recently, US biotech company Northwest Biotherapeutics has developed a brain cancer vaccine, called DCVax, which is designed to help patients' immune system to target their tumors that may prolong their life by months or, in some cases, years.5 Thus, opening a door for the development of innovative therapy for targeting glioblastoma. The vaccine is created for each patient individually by isolating dendritic cells, from their blood which is then primed with biomarkers from a sample of the patient’s tumor.6 Dendritic cells present tumor antigens to the immune system, prime T cells, and mobilize antitumor responses.6 To evaluate the safety of the vaccine and its impact on survival time in patients with Glioblastoma, a phase 3 randomized control trial was conducted.7 In this trial, 348 patients newly diagnosed with Glioblastoma were tested at King’s College Hospital and other centers around the world for 8 years.7 Patients had surgery to remove their tumors as much as possible, followed by radiation and chemotherapy as the standard treatment for Glioblastoma.7 Among these patients, two out of three were treated with the vaccine, DCVax-L, with the remaining one-third receiving a placebo.7 The astonishing result of the trial has shown that newly diagnosed patients who received the vaccine survived for 19.3 months compared to 16.5 months for those who received a placebo.8 Overall 13% of all trial participants treated with DCVax lived more than 5 years after diagnosis compared with 5.7% in the comparison group who did so.8 Moreover, this is the first time in 17 years that such a significant result has been achieved in a Phase 3 trial of a systemic treatment for newly diagnosed Glioblastoma, and it’s the first treatment in 27 years for patients with GBM recurrence.9 Thus, this development represents a major step forward in our efforts to combat this devastating disease. Based on the findings of the trials evaluating the drug’s efficacy, it has the potential to improve the quality of life for patients, especially for the elderly and those unable to have surgery. A global clinical trial has concluded that the DCVax is the world’s first vaccine to treat deadly cancerous brain tumors that could help patients to live for years.9 This breakthrough could benefit 2500 people a year in the UK being diagnosed with Glioblastoma.9 It has also been shown that this therapy can be used to treat cancers other than Glioblastoma.9 However, due to high recurrence rate and lethal outcomes, the treatment of gliblastoma has seen significant transformation, switching from an aggressive surgical strategy to a more cautious one. The endorsement of the vaccine is a commendable achievement, and it demonstrates the unwavering commitment of researchers and healthcare professionals to discovering effective treatments for such lethal disease. Furthermore, vaccine may enhance the quality of life of a patient and provides a new hope for patients and their families Thus, it is crucial that we continue to support research into Glioblastoma and the development of novel treatments so that we can envision a future where this disease is eradicated. Declaration of conflicting interests The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Funding The author(s) received no financial support for the research, authorship, and/or publication of this article. ORCID iDs Areeba Fareed https://orcid.org/0000-0001-5906-9852 Samia Rohail https://orcid.org/0000-0003-1488-0080 Alishba Adnan https://orcid.org/0000-0003-1238-6687 Abdul Moiz Khan https://orcid.org/0000-0001-9796-8867 Footnotes Author’s noteNot commissioned, externally peer reviewed. ContributorshipAreeba Fareed and Samia Rohail wrote the draft. Alishba Adnan and Abdul Moiz Khan proofread it. All authors reviewed and edited the manuscript and approved the final version of the manuscript. Data availabilityNo new dataset generated. References 1. Aans.org. Available from: https://www.aans.org/Patients/Neurosurgical-Conditions-and-Treatments/Glioblastoma-Multiforme%5d (cited 9 April 2023). GO TO REFERENCE Google Scholar 2. Liau LM, Ashkan K, Brem S, et al. Association of autologous tumor lysate-loaded dendritic cell vaccination with extension of survival among patients with newly diagnosed and recurrent glioblastoma: a phase 3 prospective externally controlled cohort trial: a phase 3 prospective externally controlled cohort trial. JAMA Oncol 2023; 9(1): 112–121. Available from: https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847 (cited 9 April 2023).
PubMed Google Scholar 3. Pelc C. Experimental cancer vaccine both treats and prevents brain cancer in mice [Internet]. East Sussex, UK: Medical News Today, 2023. Available from: https://www.medicalnewstoday.com/articles/experimental-cancer-vaccine-both-treats-and-prevents-brain-cancer-in-mice (cited 9 April 2023). GO TO REFERENCE Google Scholar 4. Rong L, Li N, Zhang Z. Emerging therapies for glioblastoma: current state and future directions. J Exp Clin Cancer Res 2022; 41(1): 142. (cited 9 April 2023). GO TO REFERENCE Crossref PubMed Google Scholar 5. Aldape K, Brindle KM, Chesler L, et al. Challenges to curing primary brain tumours. Nat Rev Clin Oncol 2019; 16(8): 509–520. Available from: https://www.nature.com/articles/s41571-019-0177-5 (cited 9 April 2023).
Crossref PubMed Google Scholar 6. Technology Networks. Brain cancer vaccine shown to extend patient survival [Internet]. Sudbury, UK: Technology Networks, 2022. Available from: https://www.technologynetworks.com/vaccines/news/brain-cancer-vaccine-shown-to-extend-patient-survival-367721 (cited 9 April 2023).
Google Scholar 7. Clinicaltrials.gov. Study of a drug [DCVax®-L] to treat newly diagnosed GBM brain cancer - full text view - Clinicaltrials.gov [internet]. Bethesda, MD: Clinicaltrials.gov, 2023. Available from: https://clinicaltrials.gov/ct2/show/NCT00045968 (cited 9 April 2023).
Google Scholar 8. Campbell D. Vaccine shown to prolong life of patients with aggressive brain cancer. London, UK: The guardian [Internet], 2022. Available from: https://www.theguardian.com/science/2022/nov/17/vaccine-shown-to-prolong-life-patients-aggressive-brain-cancer-trial-glioblastoma (cited 9 April 2023).
Google Scholar 9. Delgado-Martín B, Medina MÁ. Advances in the knowledge of the molecular biology of glioblastoma and its impact in patient diagnosis, stratification, and treatment. Adv Sci 2020; 7(9): 1902971.
Crossref Google Scholar📷 0 Share Reply/Post Keep Last Read More Next 10 Prev NextNWBONorthwest Biotherapeutics Inc (QB)0.615 0.011 (1.82%)Volume:1,013,957Day Range:0.6011 - 0.62Bid:0.61Ask:0.615Last Trade Time:3:59:10 PM EDTTotal Trades:378

• 1D
• 1M
• 3M
• 6M
• 1Y
• 5Y

📷

NWBO Detailed Quote

Recent NWBO News

• Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 04/05/2023 11:32:06 PM
• Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 04/05/2023 01:31:24 PM
• Nightfood, Inc. (OTCQB: NGTF) now in Sonesta International Hotels Multiple Brands • InvestorsHub NewsWire • 03/13/2023 11:35:55 AM
• Annual Report (10-k) • Edgar (US Regulatory) • 02/28/2023 09:31:58 PM
• Annual Statement of Changes in Beneficial Ownership (5) • Edgar (US Regulatory) • 02/07/2023 10:55:54 PM
• Current Report Filing (8-k) • Edgar (US Regulatory) • 01/13/2023 09:34:51 PM
• Current Report Filing (8-k) • Edgar (US Regulatory) • 01/06/2023 09:42:13 PM
• Additional Proxy Soliciting Materials (definitive) (defa14a) • Edgar (US Regulatory) • 12/23/2022 10:24:51 PM
• Additional Proxy Soliciting Materials (definitive) (defa14a) • Edgar (US Regulatory) • 12/16/2022 06:40:40 PM
• Proxy Statement (definitive) (def 14a) • Edgar (US Regulatory) • 12/05/2022 12:01:37 PM
• Northwest Bio Accuses Market Makers of Share Price Manipulation • TipRanks • 12/01/2022 03:29:04 PM
• Proxy Statement - Notice of Shareholders Meeting (preliminary) (pre 14a) • Edgar (US Regulatory) • 11/25/2022 10:30:31 PM
• Quarterly Report (10-q) • Edgar (US Regulatory) • 11/09/2022 09:31:44 PM
• Acquisition Completed: Endexx (EDXC)'s HYLA Secures 200k+ Unit Order; 4,500 Puffs per Unit • InvestorsHub NewsWire • 09/27/2022 01:33:31 PM
• Amended Annual Report (10-k/a) • Edgar (US Regulatory) • 06/30/2022 09:09:33 PM

More NWBO News

InvestorsHub NewsWire
CGrowth Capital Consolidates Lithium Tenement Portfolio in Tanzania Amid Renewed Mining Confidence • CGRA • May 25, 2023 11:05 AM
Interactive Strength Inc. d/b/a FORME Launches European Expansion Plan by Focusing on Strategic Partnership with SIGNA Sports United • TRNR • May 24, 2023 10:14 AM
Nextech3D.ai Game-Changing Generative-AI CAD 3D Design Studio Toggle3D.ai Primed For $7 Million June IPO • NTAR • May 24, 2023 10:00 AM
Kaya Holdings, Inc.'s V.P. Bryan Arnold Among First Ten (10) State Licensed Psilocybin Facilitators in U.S.A. • KAYS • May 24, 2023 9:48 AM
ILUS Confirms Its First Quarter of 2023 Results • ILUS • May 23, 2023 9:34 AM
SKYX Set to Join Russell 2000® and Russell 3000® Indexes • SKYX • May 23, 2023 8:56 AM
Start posting your company's newsOnly $200 per official company press release!

Hi. I just came back from a two week trip. I lived in Osaka and Tokyo some years ago so this trip was really meeting up with old friends again and also going for some new adventures.
It's so affordable now (if you have USD, which is strong against the yen). I ate and drank so well! I went to a lot of izakaya, tried various local and regional specialties (unagi around Hamamatsu, akafuku in Ise, for example). All for waaaayyyyy cheaper than what I spend at home in Philly or NYC.
I also did a bit of biking. In Japan you often get a mamachari, which is like "your momma's chariot", or a bike your Mom would ride. With a basket. But hey they're fun for just cruising around! I've decided biking around the countryside is one of my favorite travel activities.
The main idea of this trip was:

• Tokyo - catch up with friends and visit my favorite hang out places and restaurants.
• Hamamatsu - I went to a beach at 7am, rented a bike, and biked around the Lake Hamana area. I took three trains, two buses, and a ferry to Ise. Yes obviously it takes longer than shinkansen to Nagoya, but this is the scenic route lol.
• Going to Ise was about Ise-jingu, of course.
• One night in Nabari. I wanted to see Akame 48, where there are a bunch of waterfalls.
• Nara - last time I was there was 19 years ago. I spent just one day doing the usual stuff in Nara-koen and two days doing a bunch of other things on the outskirts.
• Osaka - it was great to be back, but mainly I was there to get shinkansen back to Tokyo.

Some more details:
Tokyo

• I splurged and stayed at the Shiba Park Hotel. Shiba Park is near Hamamatsu-cho, which is easily accessible from Haneda via the monorail.
• I went to a Kanda matsuri (festival) that involved people parading around omikoshi (portable shrine). They're really fun if you haven't seen. While there, by chance I came upon a kabuki theater and an usher convinced me to buy a ticket. Really colorful and dramatic.
• I hit up some museum favorites such as the Tokyo Photographic Art Museum in Ebisu (I used to live across the street) and Ōta Memorial Museum of Art in Harajuku (all ukiyo-e, which I love).
• Tip: if you are in Tokyo Station, have time to kill, and like art, there's a gallery near the north gate. Currently it's Japanese Paintings of Modern Osaka.

Hamamatsu

• Probably not on most people's radar, it's not a must-see city. I took a local train to Maisaka, walked to the ocean, walked around more, and found a bike rental place in Bentenjima.
• Biked up to Hamanako Garden Park. It's all about flowers. Then biked farther up to Kanzanji-cho and ate some delicious unagi (eel).
• The city is not super exciting but the Museum of Musical Instruments is really cool. They have a room with instruments you can rock out on. I banged on a djembe and plucked a koto.
• As part of the scenic route to Ise, I took trains and buses out to Irago, then ferry across to Toba, and local Kintetsu train up to Ise.

Ise

• Stayed in a ryokan near the train station. The main thing here is Ise-jingu, the most sacred shrine in Japan, the holiest of holies. Took advantage of lingering jet lag to wake up early and get in at 6am. It opens at 5!
• The early morning hours are great. The main strip leading up to Geku wasn't that crowded even in the afternoon, although the main strip outside Naiku - okage yokocho - started to get busy after 9am.

Nabari

• A small town in Mie-ken. I had always heard about Akame 48, where there are supposedly 48 waterfalls. The day was totally rained out. I took a local train and then bus to the visitors center but the rain wasn't letting up. I had a long chat with a friendly young Japanese guy who worked there. He doesn't see many visitors lately so I think he was glad for the opportunity to chat.

Nara

• Stayed at a guest house near Nara-machi. This area is so cool - some tourists visit but still very local. Great for strolling around and checking out the shops. I did the usual Nara Park stuff for one day - Daibutsu, Nara National Museum, etc.
• I rented a bike and headed out to Toshodai-ji and Yakushi-ji. It's a slight trek but there's a small river you can bike along which was cool.
• I tried and failed to finish the yama-no-be-no-michi ("mountain area path"), as detailed in the LP book. I started too late and it was too hot. There are sign posts here and there but notably lacking where there are some forks in the road. You start from Tenri station and takes at least 30 minutes walking just to get to the start of the trail. Better planning next time.

Osaka

• Stayed at APA Hotel in Umeda, rented a bike and went out to the aquarium. That's a bit of a slog but still worth it. At night walked around the usual places like Shinsaibashi, Ame-mura, etc.
• I had time to kill before catching the shinkansen back to Tokyo so I rented a bike from the Shin-Osaka station and biked along the Yodo River. It's so nice - wide paths and great scenery.
• Tip: I was reminded of how confusing it is to navigate Umeda on the street. Don't bother. If you have to find a station or something, go underground and follow the signs!

Some expenses (USD):

• Airfare: $1500
• Hotel: $1200
• Food and drink: $700, which is simply amazing. And I ate so well!
• Transportation: $325
• Various activities: $300

My takeaway: after traveling in many places, I continue to find that some of the best experiences are those unplanned. Any trip requires plans obviously, but with a little luck and a traveler's intuition, I'm getting better at arriving at those fun spontaneous moments.
Ask me any questions. Thanks for reading.

Job description
ABOUT US
Campbells Quality Meats have a rich history within the Gippsland region. We are a retail butcher, operating for over 30 years in Gippsland and have built our brand and reputation to be synonymous with both quality and supply. With two core product offerings, we not only provide the local communities with high quality cuts and smallgood but we also have a Pet Food division, ensuring your furry friends have the best products available too!
Campbells Quality Meats are now seeking to appoint a qualified and/or experienced Meat Production Worker to join our growing team for our operations in Traralgon, Victoria, on a full-time basis.
ABOUT THE ROLE
You’ll have the opportunity to work within a dynamic team environment, utilising your skills and experience to prepare and present meat products for general consumption.
https://482jobs.com/job/meat-production-worker-australia-sponsorship-opportunities-if-required-2/

I (20sF) am part of a five member friend group and two of the friends, let’s call them Joanne and Tim, used to be in a relationship. I was always close with Joanne and Tim came into the friend group once they started dating. I’ve known these friends for nearly 4 years.
Tim was very toxic towards Joanne - manipulative, controlling, didn’t respect boundaries etc - and after just over a year of dating Joanne built up the courage to breakup with him. There were many times I listened to Joanne vent and cry about his behaviour and once she admitted to me that it was a matter of “when, not if” they broke up I supported her through this. I was so relieved for Joanne when it finally happened.
Tim and Joanne made a big show of still being friends as they claimed they didn’t want to break up the friend group. Eventually Joanne admitted to me that they had started sleeping together again, and on a group holiday I had the misfortune of walking in on them. I was naturally furious at this as me and Joanne were sharing a room and Tim should not have been there in the first place. Joanne begged my forgiveness and I let it go as I didn’t want to sour the mood while on holiday. In this period Tim was still horrible towards Joanne and she frequently came to me for advice and I began to run out of words as my advice was repeatedly ignored.
Fast forward a year and Tim has recently gotten a new girlfriend. I thought this was a good development as Tim would be less focused on Joanne and I hoped this would give Joanne permission to move on. She claimed that it didn’t bother her that Tim was in a new relationship as they hadn’t been sleeping together for a few months at that stage and that he was free to date whoever he wanted, she was just upset that he had made her promise not to be on Tinder or date anyone else after they broke up as it wasn’t fair on him however he was doing it all along.
We once again went on our annual group holiday and I noticed something odd. Joanne was being very friendly towards Tim - constantly disappearing off with him, putting her head on his shoulder on the plane. He was putting his hand on her knee at dinner, play fighting with her, and they were both constantly whispering to each other and giggling. They would be sending messages to each other on Snapchat at the dinner table and not doing a very good job at hiding it from the group. Whereas Joanne would normally rant and complain about her behaviour, she was unusually quiet about him.
One evening they disappeared away from the spa and when I eventually went up to the hotel room I found Tim and Joanne in the bathroom with the door mostly closed over. I was speechless. Tim instantly came out and held up a roll of toilet roll, claiming he was just borrowing a roll of toilet roll off of us as the cleaners hadn’t put one into the boy’s room that day (one of our other friends had mentioned that earlier in the day to be fair and Joanne had offered them our spare one). Tim joked that I must have PTSD after walking in on them last year and then jovially asked “Threesome?” before walking out laughing. Joanne swore that nothing had happened but it wasn’t a good look.
More recently since returning from holiday we had to attend a funeral. I don’t have a car so I asked Joanne for a lift. She told me she’d be at her family home outside of our city that day as it was at the weekend. I offered to get the train near to where her family live but she responded telling me not to worry as Tim would drive instead, picking me up first before her.
Oddly on the day of the funeral, she was already in the car when Tim arrived at my house. She explained that she decided to stay at her flat in our city without any further context which is surprising as she goes to her family home nearly every weekend. Her family home is on the way to the funeral anyway so it’s not as though her staying in our city was more convenient. As the day went, little comments led me to suspect that he had spent the night at her flat.
I can’t help but feel that they’re still hooking up. It’s confusing as all the evidence of a potential affair is somewhat circumstantial and I haven’t seen them do anything more explicit such as kissing or having sex.
I have been cheated on before myself so I know how much it destroys a person’s self esteem and makes it hard to enter future relationships. I feel if I were to speak up a lot of it could be explained away as just being close friends. I’m also scared that I could have false stories spread about me. I have since left the company we all used to work for and I’m concerned they would spread stories that might damage my professional reputation. Despite this I feel strongly that the new girlfriend deserves to know if Tim is having an affair.
My stance is that I will wait until I see something more physical such as making out before I tell his new girlfriend but I feel very on edge just waiting to witness something
So I come to relationship_advice with the following questions. At what point do I tell the new girlfriend? And is there anyway to go about it without repercussions for myself?
Using a throwaway as I know most of the friend group browse Reddit

My family member last year asked me to be her bridesmaid really close to her wedding because another bridesmaid had dropped out. I of course accepted even though I lived 2 states away. I made time to attend every bridal shower, bachelorette party, rehearsal dinner etc.
My hometown is a few hours away from the town the wedding was in so each time I travelled I either drove a few more hours to stay with my parents or stayed on a family members couch. For the wedding, this was not an option since so much family was coming into town, all the guest bedrooms and couches were already spoken for so i planned on getting a hotel room for the night of the wedding.
The bride asked me a few weeks in advance if I needed a hotel room since she was blocking off rooms for the band and said she would block off one extra room for me. When I called the hotel they had only one extra room besides the ones she blocked off for that night so I triple checked with her that one room was for me. She assured me one was so I changed the room into my name and put my card on file.
My boyfriend also drove from two states away to come to the wedding with me and brought my dog since no one would be home to watch her. We planned on leaving her in the pet friendly hotel during the wedding and checking on her every few hours since the hotel was super close to the reception. This was also by boyfriends first time meeting my family so we were excited.
The day of the wedding the bride tells me that I no longer have a room at the hotel because they did not book enough rooms for the band so they would be taking mine. I informed her that my boyfriend and my dog we’re already on there way to check in to the hotel and she basically said sorry they can’t check in. All other hotels close to the area were booked solid for that night and the only available room was over 30 minutes away and $300 more than what I paid. I let her know that I spent a lot of money to travel back and forth for her wedding and didn’t have the money even in my account to do so. She asked me to find somewhere else to stay, which I tried but with my boyfriend, my dog (who doesn’t get along with other dogs) and I, there was literally nowhere. She told me she didn’t know what to tell me so I told her if I no longer had a hotel room that I would be asking my boyfriend and dog to head back to my parents house hours away and I would be leaving the reception early to go home too.
She was very upset with me but I felt like I had no other choice and I feel as though it has ruined our relationship. The manager at the hotel informed me that since my name and card were already on the reservation that nobody else could check into my room and the bride had to send one of the band members to the other hotel that was farther away and more expensive.
Am I the asshole for not giving my room up?

Hi everyone, I'm sorry in advance for taking up your time. Here we go. So, last weekend, my sister (we will call her K), brother in law ( we'll call A),nephew and I went to a wedding. The wedding was of my sister's best friend ( we'll call her S), who's practically my sister since I've known her my whole life. K and A told me S invited me and told me to come with them, since I don't drive. K made a 'joke' that I wasn't intruding, since I would be babysitting my nephew the whole time, while they have fun. Before the wedding, we agreed on splitting the cost of food and drinks. After the wedding, K told me to pay half for the car gas, toll's during the trip, the food and drinks, A just smiled. I may be the AH here, since I told her she'll get half the money for food and drinks. I'm willing to pay for the food/ drinks, but what doesn't make sense to me is paying for the gas/ toll's, since they were going there anyway and it feels like they are trying to, for lack of a better word, profit off of my going to the wedding. I'm probably biased since this isn't the first time this has happened. K has been like this our whole lives and this was just something that sent me over the edge. Since the wedding was far away, we stayed in a hotel, that S and her now husband payed for (and didn't ask for us to give them the money since they invited us to the wedding). I feel like I also shouldn't pay because we are a family and I've paid for things they needed multiple times without asking for money, our dad has driven them home without a word, just so that they wouldn't have to take the bus, etc. Ask any questions, please, I'm probably forgetting some things, since I'm, quite honestly, a bit mad/ disappointed. So, AITA? Sorry for any errors, English isn't my first language.

Life's been so tough lately to the point na sa sobrang hirap, hindi ko maiyak. But this night, I got the reason to make my tears fall apart. My university finally released the list of latin honors, and I didn't make it.
I am a graduating college student, consistent honor student since junior high school. But everything changed pagtungtong ng college, totoo na it's a matter of survival na lang. Inexpect ko naman na unang taon pa lang, pero nilaban ko hanggang huli pero hindi pa rin talaga kinaya. And that mistake was not my fault, its the University and the Professor's pero ako yung nagsuffer.
I know that I can still be an honor student, other friends/classmates keep asking me kung pasok ba ako kasi kita talaga nila yung potential ko. Kaya dumadagdag tuloy yung pressure and disappointment na yun. I know I don't owe them any, pero yun talaga yung nafefeel ko. My family esp. my mom who is an OFW for 22 years never put a pressure on me, pero yun na lang kasi yung alam ko na maibibigay ko sana sa kanya na kaligayahan. Sorry ma, I failed this time. Sana sa totoong laban ng buhay, makabawi ako sayo/sa inyo.
Di ko mailabas yung nafefeel ko so dito ko na lang ira-rant, I'm keeping my image kasi na tanggap ko na nang maluwag but in reality, tatanggapin ko pa lang. I hope proud pa rin sila sa akin, kasi di ko maramdaman yun para sa sarili ko.

My husband and I are finally getting around to planning our honeymoon in Italy. We haven't traveled too much outside of the US and never to Italy. The last couple years for us have been difficult, so we are hoping to have a relaxing, enjoyable, easy trip to Italy.
We are overwhelmed with recommendations from family and friends and don't know where to start (taking advice from grandma on what to do on vacation might not be the best thing). Hoping Reddit will be able to help us if we tell you what we're looking for! Any help would be great! xo
- Recs on where to stay (locations), must-see places, and tips on how to travel to/from.
- Vibe: easy, relaxing, fun, informative.
- We want to visit in 2024, and when the weather is "nice". Meaning sunny, 80 degrees-ish.
- Hoping to be there for 8-10 days, in a few different areas.
- We'd love to spend a few days on the beach, sipping drinks, taking walks, eating, reading, just relaxing. (I'm told the Amalfi Coast is perfect for this?)
- We'd love to spend a few days exploring other areas, learning about the culture. Places that aren't hard to travel to / from.
- We don't want to bop around to too many locations / change hotels a lot.
- We don't want to spend a TON of money, but have money saved up. We're not interested in anything extravagant or too fancy, but we also don't want to stay in hostels.

Good afternoon, everybody.
(TL;DR. Ex girlfriends brother disabled my security cameras when they were collecting her things from our apartment. I can only imagine malicious reasons.)
Recently, my girlfriend and I broke up after some long standing issues came to a head. The breakup was ugly and her family is very protective of her.
Yesterday (Sunday), she asked to collect her things today (Monday) from the apartment that we both lease; including the pet rats that we both care for. I had today off for Memorial Day so asked her to delay one day so I would be at work and her family would have an uninterrupted 8+ hours to take things. She declined and we began to argue and I stated that if she wanted her things today I could put them by the side of the road and she could collect them there because I wouldn’t be leaving. She interpreted this as me threatening to put the rats outside for her to collect as well and in that panic decided they needed to come that evening before damage could be done.
Being put on the spot I started trying to figure out how to plan for her being there in the two and a half hours it would take from her parents house. My mother was already there with me to make sure I was okay and I started packing some of her things to get them out of the apartment as soon as possible as well as putting the rats into a prepared travel cage so they would be easier for them to take.
During that time, my two best friends also came over and offered to keep watch over her family to make sure things weren’t being taken that weren’t hers and that no destruction was happening of my property. After explaining the situation, my mother and I left for her house.
Now for the important part. Inside of and around our apartment I have five Blink security cameras that watch my front door, back door, parking lot, kitchen, and living room (no cameras have any substantial view of bedrooms or bathroom). The two facing the living room and kitchen were put in place because our landlord had an exterminator coming and I wanted to have evidence if there were any issues. My ex was aware of and agreed to them being placed.
While the apartment was being gone through by her family, after over an hour of them being there and me getting recordings and notifications from the cameras, her brother (who is very intelligent and tech savvy) noticed the cameras and immediately began going around toppling the cameras and eventually went to my office and disconnected my modem and routers which disconnected the cameras from their base station and stopped all recordings.
I messaged my ex later that night asking if she have given her family permission to touch the cameras and she said she had not. I have recorded proof of him tampering with the cameras. I also have a video of the entire apartment before they came showing the state of everything in it.
My question is, is there any recourse for this? The only good reason I can imagine for disabling the cameras is to avoid being seen doing something untoward that my friends didn’t catch. My instincts say that this is illegal, potentially even if she had given permission to turn them off because they are my cameras protecting my property, but regardless I can’t find any solid information online, so I thought I would ask here.

1. #Dad PROS: takes me to doctor when needed without week delays, will spend money on me, is on time when picking me up from school or other things, if I need something he will usually buy it for me, I get to be with my pet cat, doesn't make me feel guilty for asking for things like new shoes, floss, food etc.

CONS: emotinally abusive, manipulative, narcissist, says thing like I am worthless, loser brat etc. Doesn't really love me, treats me like a maid, house is always messy/never clean, has a dog that is not trained that bites and jumps (ruins clothes),only eat out and box fries + nuggets, yells about politics to me for hours and doesn't let me leave, passive aggressive.I haven't been to his house for almost half a year. I have attempted suicide before due to him.

1. #Mom PROS: Nice when she's not grumpy, buys me things but usually makes me feel bad about it, nice neighbors, I don't feel uncomfortable around her most of the time.

CONS: Yelling fits telling everyone in the house that we shouldn't live there, does drugs secretly and is horrible at hiding it, leaves with het boyfriend randomly at night leaving me at home with a 13, 11 and 10yo, is always late to picking me up for things by about 30min-1hr, sleeps in every day, drinks lots, off from work for the last couple months, refuses to buy fan in 30c weather, house is always messy, never gets anything done, doesn't register me in anything, doesn't take me to doctor, I have to ask for months before she makes an appointment, makes me feel bad for asking for bare necessities, doesn't commit to anything, unreliable, bad advice, breaks things sometimes when she's mad, we fight almost every day

1. #Auntie & Uncle# not really sure about this option... PROS: Healthy living like daily walks, healthy eating, clean house, good relationship, good living conditions. They're nice to me, I like them, have normal jobs, they're emotionally available,

CONS: They live in a different city than my current one that is 6 hours away, new school, (I have social anxiety), leaving the city I've spent my whole life in, I'll probably lose my relationship with my friend I've known since I was 4 and care deeply about, feeling guilt because I know having a kid was not in their life plan, being away from my other Auntie in my current city that I'm close with who has terminal cancer, leaving my siblings.
Honestly I'm a really shy person and a pushover. I stayed with them for a week and "we" made plans that I will be returning in the summer and getting a part-time job. I don't know if I want to follow through with that.. I don't know if they can handle someone like me who is so sick mentally compared to them. I'm a kid who comes from a messed up home, school, neighborhood and city vs their "tv like" home and family. When I'm with relatives I'm really helpful and happy looking (which is how I acted with them for the week I stayed.) I'm scared that if I stay with them they'll see my real lazy, ugly, and sick personality.
Sorry this post is everywhere, and doesn't have a lot of details or is well written. I really need help making a choice but I have literally no one to help me make this decision. I know the 3rd option is best for me. But it's really hard to decide on my own to leave everything in my life I've known including my family. If anyone wants to ask me questions about anything go ahead..

I’ve heard that in some areas it can be hard to homestead due to laws and needing permits for everything… how true is this? I’ve also heard property taxes are really high however my husband is a disabled vet so I understand we would be able to be exempt from property taxes.
If you are in PA what areas would you recommend and/or advise to stay away from?
Anywhere else you might recommend to homestead? We’re looking for somewhere with a little bit of the 4 seasons, land (obviously), affordability, greenery, homeschool friendly and job opportunities nearby.

For me, being able to meticulously analyze every social interaction I have.
When I was younger, at least that sort of helped me when breaking up with that GF or just making rational decisions over the course of my life.
Working out and developing my professional career helped me grow as a person, so now I live alone, I don't depend on anyone, I'm single but happy.
I often hang out alone, with no problems whatsoever. I've talked to many strangers that way, it seems people get really comfortable when someone hangs out alone.
So, I don't know anyone else who is like me. Most people hang out with friends, in groups, parties, their social media is really active. As for me, I just upload some photos of me and my pets lol.
I often hang out with friends but I just forget to take photos like they do, so my instagram always seems like I'm a loner.
Well, I honestly am, but I'm already used to fortunately.

I feel like some of my friends (all women) are complete idiots when it comes to dating. A few days ago I made a post about a former friend (32) which includes her really dumb dating history. Now she’s married and miserable.
I have another friend (35) who, over the past year or so, has broken up with her boyfriend multiple times and each time they get back together. He wants kids, she’s doesn’t know if she wants any (and has previously said she doesn’t). She also feels he’s being a freeloader and keeps allowing her to pay for all their trips and he lives with her for free basically. Ever heard of saying “no”?
I have another friend (36) who has expressed wanting to move to a different state because dating prospects in her hometown are nonexistent. I saw a TikTok video featuring a woman who talked about her experience going out alone to a hotel bar for happy hour. She said several men approached her while there. I thought this might be a good idea for my friend so I sent it to her. She said she needed to do “research” on where to go to 🤨. I immediately sent her a suggestion for a bar I know in NYC. The first question out of her mouth was “are there dollar signs?” aka will wealthy men be there. I (kindly) let her know maybe her main focus right now shouldn’t be money.
Dating nowadays seems awful (I’m off the market THANK GOD and am very happy in my relationship). Imo a lot of people are focused are on the wrong things and completely ignore all the essential items - aligning on values, finances, goals etc. I honestly give up trying to help my friends. Good luck to them.

Accompanying my friend, I met her friend (a guy friend). We are all in the same age and in our last year in college. I wrote this because I think its very rare to met this kind of individual and I think its worth of sharing.
At first, nagkaroon ako ng doubt kasi I find it unreal na at his age (22 or 23), he still has a curfew and he follows them pa. Ako, my curfew when I was in 10th grade is 4pm. Nung 11th and 12th, 5 pm. Nung first year college, 6 pm. Now na fourth year collge, my curfew is 7 pm pag walang pasok pero 9 pm kapag may pasok sa school since I have class till 8:30 pm. Going back to him, he's curfew is 5 pm. Na amazed ako kasi sa lahat ng taong nakilala ko, he's different. Sinusunod niya ung patakaran sa kanilang tahanan and the respect that he's giving to his elders is so admirable. Imagine at his age nagagawa niya yun? Most of the guy na nakilala ko kasi (even girls) they party and drink a lot, etc. Plus, I also learned na he doesn't drink alcohol. Narinig ko kasing sinasabihan niya ung friend ko na huwag nang uminom. He advised her to buy more nutritious drinks na lang. Wala lang. As non-drinker, ang saya lang maka-meet ng taong di rin umiinom. Nakaka-proud lang.
:these might be boring but skl